Curriculum Vitae: Michael S. Chapman

Employment & Affiliations
Professor of Chemistry, Florida State University (2003 - current).
Courtesy Appointments:
bullet Department of Biological Science and Physics Department, College of Arts & Sciences.
bullet Department of Biomedical Science, College of Medicine.
Director, Center of Excellence in Biomolecular Computer Modeling & Simulation
Member, Structural Biology Program (1993 - current).

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Education

bullet A.K.C. Divinity, University of London, Kings College, 1979 - 82.
bullet B.Sc. Cellular & Molecular Biology, University of London, Kings College, 1979 - 82, Steve Neidle research director.
bullet M.Sc. Crystallography, University of London, Birkbeck College, 1982 - 3, John Finney, research director.
bullet Ph.D. Biochemistry, University of California in Los Angeles, 1983 - 7, David S. Eisenberg, research director.
bullet Post-doctoral fellowship: Purdue University, 1988-93, Michael G. Rossmann, advisor.

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Past Employment

Associate Professor Department of Chemistry & Biochemistry, Florida State University 1998-2003
Assistant Professor Department of Chemistry, Florida State University 1993-8
Post-doctoral Associate Department of Biological Science, Purdue University; Michael Rossmann (mentor) 1988-93
Teaching Fellow Department of Chemistry & Biochemistry, UCLA 1995
Teaching Associate Department of Mathematics, Program in Computing, UCLA 1984-5
Teaching Assistant Department of Chemistry & Biochemistry, UCLA 1983-4
Research Assistant Physics Department, National Institute for Research into Dairying, UK 1979

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Honors

bulletFellow, American Association for the Advancement of Science, 2005 - .
bulletDeveloping Scholar Award, Florida State University, 2000.
bulletFlorida State University First Year Assistant Professor Award, 1994.
bulletScience & Engineering Research Council Studentship (UK), 1982-3.
bulletBritish Petroleum Education Trust Scholarship, 1979-82.
bulletFoundation Scholar, Monmouth School, 1974-9.

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Grants & Funding

Currently active

Agency ID Title Dates Direct costs Total funding
FSURF Cornerstone Program Center of Excellence: 5-1303-0633 Biomolecular Computer Modeling & Simulation
(Grant to develop new center - infrastructure, training program & faculty recruitment)		 4/22/00 - 6/30/07 $995,107 $995,107
NSF / National High Magnetic Field Lab. IHRP 5024-641-22 project 5045 Functional Dynamics of Arginine Kinase: Development of TROSY-based Spectroscopy 1/1/03 - 12/31/05 $103,198 $142,059
National Institutes of Health P01 GM064676 Membrane Protein Structural Genomics: M. tuberculosis (sub-project - T.A. Cross is P01 PI) 9/28/01 - 8/31/06 $460,725 (6.9M) $663,167 (8.1M)
National Institutes of Health R01 GM066875 Structure-Function of AAV - a Viral Gene Therapy Vector. 2/1/03 - 1/31/07 $740,000 $1,061,497

Participation in other Grants

Agency ID Title Dates Direct costs Total costs Participation
American Heart Assoc. (FL) Pre-doctoral fellowship (Eliza Ruben): A Computational Study of Arginine Kinase Catalysis 7/1/04 - 6/30/06 $40,000 $40,000 Faculty PI
American Heart Assoc. (FL) Pre-doctoral fellowship (Omar Davulcu): 0415115B Functional Dynamics of Arginine Kinase 7/1/04 - 6/30/06 $40,000 $40,000 Faculty PI
National Institutes of Health S10-RR020919 (K. Taylor, PI) Purchase of a large format CCD camera for 3-D EM 4/1/05 - 3/31/06 $281,300 $281,300 Co-PI
American Heart Assoc. (FL) Pre-doctoral fellowship (Jason O’Donnel): 0515201B Mapping Adeno-associated virus-2 cellular receptor binding sites using Cryo-Electron Microscopy 7/1/05 – 6/30/07 $42,000 $42,000 Faculty PI
American Heart Assoc. (FL) Pre-doctoral fellowship (Heather Ongley): 0515203B Structural Studies of Adeno-associated Virus Serotypes 3b and 6 7/1/05 – 6/30/07 $42,000 $42,000 Faculty PI

Last updated 12/07/05

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Past funding

Agency ID Title Dates Direct costs Total costs
American Heart Assoc. (FL) Pre-doctoral fellowship (Jeff Bush): 0315101B Lombricine kinase structure & specificity 7/1/03 - 6/30/05 $38,000 $38,000
National Institutes of Health R01 GM55837 Phosphagen Kinase Structure, Mechanism and Specificity 3/1/98 - 2/28/04 $507,440 $745,743
American Cancer Society RPG-99-356-01-GMC Towards an Anti-Cancer Virus: Structure & Function of Adeno-Associated Virus 7/1/99 - 6/30/03 $300,000 $375,000
National Science Foundation DBI 98-08098 Macromolecular Structure: Crystallographic Structure Determination/Refinement using Atomic Electron Density Functions, and Optimization of Appropriate Force Fields for Analysis 10/1/98 - 9/30/02 $211,553 $300,000
National Science Foundation DBI 98098098 / 0118088 Research Opportunity Award Supplement to DBI 98-08098 5/1/01 - 9/30/02 $21,529 $31,432
National Institutes of Health   Gordon Research Conference: Diffraction Methods in Structural Biology July 2002 $5,000 $5,000
Florida State University   President's Developing Scholar Award 7/1/00 - 6/30/01 $6,000 + $6,000(match) $12,000
National Science Foundation BIR 94-18741 Applications of Real-Space Refinement for Macromolecular Structure Analysis 4/1/95 - 3/31/99 $226,080 $325,981
Florida State University CRC COFRS Atomic Interactions in Macromolecules 5/7/98 - 8/5/98 $7,778 $7,778
American Heart Association, FL division 9701728 Phosphagen Kinase Structure and Function: Improved Creatine Kinase Immunoassay for the Diagnosis of Heart Attacks 7/1/97 - 3/31/98 (terminated pro rata when replaced by NIH grant) $89,998 $99,997
Florida State University CRC Planning Grant Adeno Associated Virus: Atomic Structure Leading to Imrpoved Vectors for Gene Therapy 11/01/96 - 10/31/97 $12,062 (incl. match) $12,062
American Cancer Society, Florida F-95FSU-2 Towards Anti-tumor Viruses I: Crystallization of Adeno Associated Virus 02/01/96 - 01/31/97 $22,000 $22,000
Florida State University CRC Planning Grant Improved Diagnosis of Recent Heart Attacks 11/01/95 - 10/31/96 $11,934 (incl. match) $11,934
Florida State University CRC First Year Assistant Professor Award 5/94 - 8/94    
Last updated 10/25/05

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Professional Activities

Vice Chair: Gordon Research Conference

Diffraction Methods in Molecular Biology, July 2000

Chair: Gordon Research Conference

Diffraction Methods in Structural Biology, July  2002

4th FSU Structural Biology Symposium, January 2001:

Computational Structural Biology - From Simulation to Experiment and Back

Chair, Organizing committee

SouthEast Collaborative Regional Access Team (SERCAT)

bulletA consortium of Southeastern States + NIH intramural research program in a ca. $15.6M project to build two x-ray beam lines at the Advanced Photon Source at the Argonne National Laboratory, Nr. Chicago.
bulletExecutive Board (99 - ); Operation and Management Planning Committee (99 - 02); Finance committee (02 - ).

Journal Referee

Acta Crystallographica, Advances in Microbiology, Biochimica & Biophysica Acta, J. Biological Chemistry, J. Crystal Growth, J. Molecular Biology, J. Structural Biology, Nature Structural Biology, Protein Science, Structure, Trends in Microbiology.

Grant Review

Panel memberships (permanent & temporary), Special panels, Consultant

National Institutes of Health,           
bulletNeurological Sciences III, 1997.
bulletExperimental Virology, 1997.
bulletSpecial Panel, 2000.
bulletNational Institute General Medical Sciences - Structural Genomic Special Panel, 2001, panel chair.
bulletNational Center for Research Resources, 2001, 02 & 03, panel chair.
bulletSpecial Panel, 2004.
bulletVirology A Panel, 2004.
bulletMacromolecular Structure & Function C, 2005 - 2008.

Ad Hoc Reviews

bullet

International Human Frontier Science Program, 1994-5.            

bullet

Petroleum Research Fund, 1996.

bullet

Cornell High Energy Synchrotron Source, 1999.

bullet

Welcome Foundation / UK government, 2000.

bullet

National Science Foundation (MCB), 2000-1.

Lecturer

bullet

International Union of Crystallography Macromolecular Computing School (1996)

bullet

NATO Advanced Study Institute on Direct Methods for Solving Macromolecular Structures (1997)

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University Activities

Florida State University

Current

  

Past

  
Co-director, Program in Computational Biology, School of Computational Science & Information Technology 1999 - 2003 Computational Science & Engineering – Executive & Curriculum committees. 1995 - 1999
School of Computational Science and Information Technology – Executive committee. 1999 – 2003 Provost's Travel Grant Committee 1998 - 01
Faculty search committees, chair 2000 - 03    

College of Arts & Sciences

Current

  

Past

  

  Teaching Fellowship / Dissertation Fellowship Committee 1999 - 2000

Department of Chemistry & Biochemistry

Current

  

Past

  
    Advisor, Biochemistry Major 1998 – 9
Committees:
  
 
  
Chair – search for Endowed Chair in Biocomputational Chemistry. 1999 - Faculty search (3) 1995 - 9
Faculty addition 1997 - Undergraduate Curriculum & Advising 1998 - 9
    Faculty Merit Evaluation 1997
    Capital Resources & Space 1994 - 9
    Computing 1994 - 7
    Seminar 1993-5; 1996-7

Institute of Molecular Biophysics & Structural Biology Program

Associate Director 1998 - 2001    
Committees:
      
Executive 1994-6; 1997 - 2001; 2003 - Director nomination, chair 1997
RTG Curriculum, chair 1996 - 2002 Faculty search (7) 1993 - 6
Biosafety 1996 - 2001 Building 1993 - 7
Eppes Professorship search 2000 - 2001 Cell Culture 1996 - 8
Director Search 2004 - 2005    

Last updated 11/16/04

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Publications

PubMed Listing (with available abstracts / text)

  1. Chapman, M. S., Smith, W. W., Suh, S. W., Cascio, D., Howard, A., Hamlin, R., Xuong, N. H. & Eisenberg, D. (1986). Structural studies of RuBisCO from tobacco. Phil. Trans. Roy. Soc. Lond. B313, 367-378.
  2. Chapman, M., Suh, S. W., Cascio, D., Smith, W. W. & Eisenberg, D. (1987). Sliding-layer conformational change limited by quaternary structure in plant RuBisCO. Nature 329, 354-356.
  3. Eisenberg, D., Almassy, R. J., Janson, C. A., Chapman, M. S., Suh, S. W., Cascio, D. & Smith, W. W. (1987). Some Evolutionary Relationships of the Primary Biological Catalysts Glutamine Synthetase and RuBisCO. Cold Spr. Har. Symp. Quant. Biol. LII, 483-90.
  4. Eisenberg, D., Chapman, M. S., Suh, S. W., Cascio, D. & Smith, W. W. (1987). The Path of the Polypeptide Backbone of Ribulose-1,-5-bis-phosphate from Nicotiana tabacum. In International Workshop on Ribulose-1,-5-bis-phosphate carboxylase-oxygenase (Bohnert, H. J. & Jensen, R. G., eds.). University of Arizona Press, Tuscon, AZ.
  5. Suh, S. W., Cascio, D., Chapman, M. S. & Eisenberg, D. S. (1987). A Crystal Form of Ribulose-1,-5-bis-phosphate Carboxylase--Oxygenase from Nicotiana tabacum in the Activated state. J. Mol. Biol. 197, 363-365.
  6. Chapman, M. S., Suh, S. W., Curmi, P. M. G., Cascio, D., Smith, W. W. & Eisenberg, D. S. (1988). Tertiary Structure of Plant RuBisCO: Domains and their Contacts. Science 241, 71-74.
  7. Hajdu, J., Clifton, I. J., Hadfield, A., Howell, P. L., Almo, S. C., Petsko, G. A., Greenhough, T. J., Shrive, A. K., Campbell, J. W., Parson, M., Harrison, S. C., Liddington, R. C., Rossmann, M. G. & Chapman, M. (1989). Daresbury Annal.
  8. Kim, S., Smith, T. J., Chapman, M. S., Rossmann, M. G., Pevear, D. C., Dutko, F. J., Felock, P. J., Diana, G. D. & McKinlay, M. A. (1989). Crystal Structure of Human Rhinovirus Serotype 1A (HRV1A). J. Mol. Biol. 210, 91-111.
  9. Chapman, M. S., Giranda, V. L. & Rossmann, M. G. (1990). The Structures of Human Rhinovirus and Mengo Virus: Relevance to Function and Drug Design. Sem. Virol. 1, 413-27.
  10. Giranda, V. L., Chapman, M. S. & Rossmann, M. G. (1990). Modelling of the Human Intercellular Adhesion Molecule-1, the Human Rhinovirus Major Group Receptor. Proteins 7, 227-33.
  11. Giranda, V. L., Chapman, M. S., Rossmann, M. G., Staunton, D. & Springer, T. A. (1990). Modelling of the C1 Intercellular Adhesion Molecule 1 (ICAM-1), the Human Rhinovirus Major Group Receptor. In International Symposium on Positive Strand RNA Viruses, Vienna, Austria.
  12. Chapman, M. S., Minor, I., Rossmann, M. G., Diana, G. D. & Andries, K. (1991). Human rhinovirus 14 complexed with antiviral compound R 61837. J. Mol. Biol. 217, 455-63.
  13. Tsao, J., Chapman, M. S., Agbandje, M., Keller, W., Smith, K., Wu, H., Luo, M., Smith, T. J., Rossmann, M. G., Compans, R. W. & Parrish, C. (1991). The Three-Dimensional Structure of Canine Parvovirus and its Functional Implications. Science 251, 1456-1464.
  14. Chapman, M. S., Tsao, J. & Rossmann, M. G. (1992). Ab initio Phase Determination for Spherical Viruses: Parameter Determination for Spherical Shell Models. Acta Crystallogr. A48, 301-312.
  15. Mallamo, J. P., Diana, G. D., Pevear, D. C., Dutko, F. J., Chapman, M. S., Kim, K. H., Minor, I., Oliveira, M. & Rossmann, M. G. (1992). Conformationally Restricted Analogues of Disoxaril: A comparison of the Activity against Human Rhinovirus Type 14 and 1A. J. Med. Chem. 35, 4690-4695.
  16. Tsao, J., Chapman, M. S. & Rossmann, M. G. (1992). Ab initio Phase Determination for Viruses with High Symmetry: A Feasibility Study. Acta Crystallogr. A48, 293-301.
  17. Tsao, J., Chapman, M. S., Wu, H., Agbandje, M., Keller, W. & Rossmann, M. G. (1992). Structure Determination of Monoclinic Canine Parvovirus. Acta Crystallogr. B48, 75-88.
  18. Chapman, M. S. (1993). Mapping the Surface Properties of Macromolecules. Prot. Sci. 2, 459-469.
  19. Chapman, M. S., Kim, K. H. & Rossmann, M. G. (1993). Structural Comparisons of Several Antiviral Agents Complexed with Human Rhinoviruses of Different Serotypes. Antiviral News 1, 53-53.
  20. Chapman, M. S. & Rossmann, M. G. (1993). Structure, Sequence and Function Correlations among Parvoviruses. Virology 194, 491-508.
  21. Chapman, M. S. & Rossmann, M. G. (1993). Comparison of Surface Properties of Picornaviruses: Strategies for hiding the Receptor Site form Immune Surveillance. Virology 195, 745-765.
  22. Kim, K. H., Willingmann, P., Gong, Z. X., Kremer, M. J., Chapman, M. S., Minor, I., Oliviera, M. A., Rossmann, M. G., Andries, K., Diana, G. D., Dutko, F. J., McKinlay, M. A. & Pevear, D. C. (1993). A comparison of the anti-rhinoviral drug binding pocket in HRV14 and HRV1A. J. Mol. Biol. 230, 206-227.
  23. Chapman, M. S. (1994). Sequence Similarity Scores and the Inference of Structure/Function Relationships. Computer Applications in the Biosciences (CABIOS) 10, 111-119.
  24. Chapman, M. S. (1995). Restrained Real-Space Macromolecular Atomic Refinement using a New Resolution-Dependent Electron Density Function. Acta Crystallogr. A51, 69-80.
  25. Chapman, M. S. & Rossmann, M. G. (1995). Single-stranded DNA-protein interactions in Canine Parvovirus. Structure 3, 151-62.
  26. Hadfield, A., Hajdu, J., Chapman, M. S. & Rossmann, M. G. (1995). Laue Diffraction Studies of Human Rhinovirus 14 and Canine Parvovirus. Acta Crystallogr. D51, 859-70.
  27. Chapman, M. S. (1996). Cross-validation R-factors and their use in comparing the qualities of refined models for the DNA-containing and empty capsids of canine parvovirus. Acta Crystallogr. D52, 140-2.
  28. Chapman, M. S. & Rossmann, M. G. (1996). Structural Refinement of the DNA-containing Capsid of Canine Parvovirus using RSRef, a Resolution-Dependent Stereochemically Restrained Real-Space Refinement Method. Acta Crystallogr. D52, 129-42.
  29. Xie, Q. & Chapman, M. S. (1996). Canine parvovirus capsid structure, analyzed at 2.9 Å resolution. J. Mol. Biol. 264, 497-520.
  30. Zhou, G., Parthasarathy, G., Somasunduram, T., Ables, A., Roy, L., Strong, S. J., Ellington, W. R. & Chapman, M. S. (1997). Expression, Purification from Inclusion Bodies, and Crystal Characterization of Transition State Analog Complex of Arginine Kinase: a Model for Studying Phosphagen Kinases. Prot. Sci. 6, 444-9.
  31. Blanc, E. & Chapman, M. S. (1997). RSRef: Interactive real-space refinement with stereochemical restraints for use during model-building. J. Appl. Cryst. 30: 566-7.
  32. Chapman, M. S. & Blanc, E. (1997). Potential use of Real Space Refinement in Protein Structure Determination. Acta Crystallogr. D53, 203-6.
  33. Chapman, M. S. (1998). Watching "One's" Ps and Qs: Promiscuity, Plasticity and Quasi-Equivalence in a T=1 virus. Biophys. J. 74: 639-44.
  34. Chapman, M. S. (1998). Introduction to the use of non-crystallographic symmetry in phasing. In Direct Methods for Solving Macromolecular Structures (Fortier, S., ed.), pp. 99-108. Kluwer, Dortrecht, Netherlands.
  35. Chapman, M. S., Blanc, E., Johnson, J. E., McKenna, R., Munshi, S., Rossmann, M. G. & Tsao, J. (1998). Use of non-crystallographic symmetry for ab initio phasing of virus structures. In Direct Methods for Solving Macromolecular Structures (Fortier, S., ed.), pp. 433-442. Kluwer, Dortrecht, Netherlands.
  36. Blanc, E., Chen, Z. & Chapman, M. S. (1998). Real-Space Refinement Using RSRef. In Direct Methods for Solving Macromolecular Structures (Fortier, S., ed.), pp. 513-9. Kluwer, Dortrecht, Netherlands.
  37. Zhou, G., Wang, J., Blanc, E. & Chapman, M. S. (1998). Determination of the Relative Precision of Atoms in a Macromolecular Structure. Acta Crystallographica D54, 391-9.
  38. Zhou, G., Somasundaram, T., Blanc, E., Parthsarathy, G., Ellington, W. R. & Chapman, M. S. (1998). Transition state structure of arginine kinase: Implications for catalysis of bimolecular reactions. Proceedings of the National Academy of Sciences, USA 95, 8449-54.
  39. Chen, Z., Blanc, E. & Chapman, M. S. (1998). Real Space Molecular Dynamics Refinement. Acta Crystallographica D55: 464-8.
  40. Chen, Z., Blanc, E. & Chapman, M. S. (1999). Improved free R-factors for the cross-validation of structures. Acta Crystallographica D55: 219-224.
  41. Zhou, G., Somasundaram, T., Blanc, E. & Chapman, M. S. (1999). Critical Initial Real Space Refinement in the Structure Determination of Arginine Kinase. Acta Crystallographica D55: 835-845
  42. Zhou, G., Ellington, W.R. & Chapman, M.S. (2000). Induced Fit in Arginine Kinase. Biophys J 78: 1541-1550.
  43. Bertram, R., J. R. Quine, M. S. Chapman and T. A. Cross (2000). “Atomic Refinement Using Orientational Restraints from Solid-State NMR.” J. Magnetic Resonance, 147: 9-16.
  44. Blanc, E., G. Zhou, Z. Chen, Q. Xie, J. Tang, J. Wang, and M.S. Chapman. 2001. Electron Density Representation and Real Space Refinement (New tricks from an old dog). In: Watenpaugh, K.D., and P.E. Bourne, editors. Crystallographic Computing 7: Proceedings of the IUCr Macromolecular Computing School, 1996. Corby, UK: Oxford University Press..
  45. Gerstein, M., F. Richards, M.S. Chapman, and M. Connolly. 2001. Protein surfaces and volumes: measurement and use. In: Rossmann, M.G., and E. Arnold, editors. International Tables for Crystallography. Crystallography of Biological Molecules. Dortrecht, Netherlands: Kluwer Academic Publishers. p 531-45 (Cpt. 22.1).
  46. Chen, L.F., E. Blanc, M.S. Chapman, and K.A. Taylor. 2001. Real space refinement of acto-myosin structures from sectioned muscle. J Struct Biol 133:221-32.
  47. Chen, Z., and M.S. Chapman. 2001. Conformational Disorder of Proteins Assessed by Real-Space Molecular Dynamics Refinement. Biophys J 80:1466-1472.
  48. Korostelev, A., Bertram, R., and Chapman, M.S. 2002. Simulated Annealing Real-Space Refinement as a Tool in Model Building. Acta Crystallogr. D58: 761-767.
  49. Bubb, M.R., Govindasamy, L., Yarmola, E.G., Vorobiev, S.M., Almo, S.C., Somasundaram, T., Chapman, M.S., Agbandje-McKenna, M., and McKenna, R. 2002. Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution. J Biol Chem 277: 20999-21006.
  50. Fabiola, F., Bertram, R., Korostelev, A., and Chapman, M.S. 2002. An improved hydrogen bond potential: impact on medium resolution protein structures. Protein Sci 11: 1415-1423.
  51. Xie, Q., Bu, W., Bhatia, S., Hare, J., Somasundaram, T., Azzi, A., and Chapman, M.S. 2002. The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy. Proc Natl Acad Sci U S A 99: 10405-10410.
  52. Yousef, M.S., Fabiola, F., Gattis, J., Somasundaram, T., and Chapman, M.S. 2002. Refinement of Arginine Kinase Transition State Analogue Complex at 1.2 Å resolution; mechanistic insights. Acta Crystallogr. D. Biol. Crystallogr. 58: 2009-2017.
  53. Yousef, M.S., Clark, S., Pruett, P.S., Somasundaram, T., Ellington, W.R., and Chapman, M.S. 2003. Induced Fit in Guanidino Kinases - Comparison of Substrate-free and Transition State Analog Structures of Arginine Kinase. Protein Sci.  12: 103-111.
  54. Xie, Q., T. Somasundaram, S. Bhatia, W. Bu, and M.S. Chapman, Structure determination of adeno-associated virus 2: three complete virus particles per asymmetric unit. Acta Crystallogr D Biol Crystallogr, 2003. 59: 959-70.
  55. Gao, H., J. Sengupta, M. Valle, A. Korostelev, N. Eswar, S.M. Stagg, P. VanRoey, R.K. Agrawal, S.C. Harvey, A. Sali, M. Chapman, and J. Frank, Study of the Structural Dynamics of the E. coli 70S Ribosome Using Real Space Refinement. Cell, 2003. 113: 789-801.
  56. Chapman, M.S., and Liljas, L. 2003. Structural Folds of Viral Proteins. In Advances in Protein Chemistry. (eds. W. Chiu, and J.E. Johnson), 64: 125-196. Academic Press.
  57. Pruett, P.S., A. Azzi, S.A. Clark, M. Yousef, J.L. Gattis, T. Somasundaram, W.R. Ellington, and M.S. Chapman, The putative catalytic bases have, at most, an accessory role in the mechanism of arginine kinase. J Biol Chem, 2003. 29: 26952-7.
  58. Bertram, R., T. Asbury, F. Fabiola, J. R. Quine, T. A. Cross and M. S. Chapman (2003). "Atomic Refinement with Correlated Solid-State NMR Restraints." Journal of Magnetic Resonance, 2003. 163: 300-9.
  59. Chen, J.Z, Furst, J., Chapman, M.S., Grigorieff, N. 2003.  Low Resolution Refinement in Electron Microscopy.  Journal of Structural Biology, 144: 144-151.
  60. Azzi, A., Clark, S.A., Ellington, W.R., and Chapman, M.S. 2004. The Role of Phosphagen Specificity Loops in Arginine Kinase. Protein Sci. 13: 575-585.
  61. Gattis, J. L., E. Ruben, Fenley, M.O., Ellington, W.R., and Chapman, M.S (2004). "The active site cysteine of arginine kinase - structural and functional analysis of partially active mutants." Biochemistry, 43: 8680-8689.
  62. Xie, Q., Hare, J., Bu, W., Jackson, W., Turnigan, J., and Chapman, M. S. (2004) Large-scale Preparation, Purification and Crystallization of Wild-type Adeno-Associated Virus 2, Journal of Virological Methods, 122: 17-27
  63. Korostelev, A., Fenley, M. O., and Chapman, M. S. (2004) Impact of a Poisson-Boltzmann Electrostatic Restraint on Protein Structures Refined at Medium Resolution, Acta Crystallographica D, Biological Crystallography, 60: 1786-1794.
  64. Quine, J.R., Cross, T.A., Chapman, M.S. and Bertram, R., 2004. Mathematical Aspects of protein structure determination with NMR orientational restraints. Bull. Math. Biol. 66: 1705-1730.
  65. 65. Fabiola, F. and Chapman, M.S. (2005) Fitting of High Resolution Structures into Electron Miscroscopy Reconstruction Images, Structure, 13: 389-400.
  66. 69. Davulcu, O., S. A. Clark, M. S. Chapman and J. J. Skalicky (2005). "Main chain 1H, 13C, and 15N resonance assignments of the 42 kDa enzyme arginine kinase." Journal of Biological NMR, 32: 178.
  67. Ruben, E. A., Evanseck, J. D., and Chapman, M. S. (2006) A theoretical study of N-phosphoryl-guanidinium tautomers - influences of hyperconjugation on N-P bond strength, Journal of the American Chemical Society, 127: 17789-17798.
  68. Chapman, M.S., and Agbandje-McKenna, M. 2006. Atomic structure of viral particles. In Parvoviruses. (eds. M.E. Bloom, S.F. Cotmore, R.M. Linden, C.R. Parrish, and J.R. Kerr), pp107-123. Hodder Arnold, London.
  69. Agbandje-McKenna, M., and Chapman, M.S. 2006. Structure-function relationships. In Parvoviruses. (eds. M.E. Bloom, S.F. Cotmore, R.M. Linden, C.R. Parrish, and J.R. Kerr), pp125-139. Hodder Arnold, London.
  70. Chapman, M. S. (2006) The Structural Enzymology of Arginine Kinase and its Implications for Creatine Kinase, in Creatine kinase biochemistry, physiology, structure and function (Vial, C., Ed.), NovaScience, New York, in press.
  71. Fabiola, F., Korostelev, A. & Chapman, M. S. Cross-validation with Over-sampled Structure Factors. Acta Crystallogr D Biol Crystallogr, accepted (2006).
  72. Quine, J.R., Achuthan, S., Asbury, T., Bertram, R., Chapman, M.S., Hu, J. and Cross, T.A., 2006. Intensity and mosaic spread analysis from PISEMA tensors in solid state NMR. Journal of Magnetic Resonance, accepted.
  73. Blanc, E., Giranda, V., Alexander, R.S., Pevear, D.C., Grorke, J., Gattis, J., and Chapman, M.S. 2004. The 2 Å Structure of Human Rhino Virus 50. Structure in preparation.

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Last updated 12/22/05