About Molecular Biophysics at FSU
The Institute of
Molecular Biophysics
(IMB) at Florida State University is
associated with the Graduate Program in Molecular
Biophysics (MOB). The Institute of
Molecular Biophysics has a long history as a unique
interdisciplinary research unit dedicated to the
application of physical and chemical principles to the
investigation of biological phenomena. The seeds of the
Institute were sown in 1959 by a group of chemists,
biologists, physicists, psychologists, and other campus
scientists who foresaw the need for close-knit cooperation
among traditional disciplines in the rapidly evolving
research area of molecular biology. This group, led by
Professor Michael Kasha and strongly supported by
University and State officials, actively sought financial
resources to establish a truly integrated research program
in Molecular Biophysics. This concept was enthusiastically
endorsed by the Atomic Energy Commission which, in 1960,
awarded the Institute a five-year grant of over $3 million
for research personnel and equipment. Additional efforts
spearheaded by Professors Kasha and Leland Shanor, secured
matching building funds from the National Institutes of Health and
the State of Florida to provide a permanent home for the
program. Construction of the Institute of Molecular
Biophysics building in 1962 provided 50,500 square feet of
space for 12 professors and a total staff of over 100
researchers. The Institute building was one of the first in
the FSU Science Center and subsequently served, both
symbolically and physically, as the hub for the
multimillion dollar constellation of research and teaching
buildings of the Chemistry, Biological Science, Psychology, and Physics departments.
The
early stage of generous funding provided not only for
highly advanced equipment and technically superior
facilities but also for many new permanent and visiting
professorships, postdoctoral and predoctoral research
positions. Scientists associated with the Institute have
been one of its greatest strengths. Two of the
Institute’s past Directors, Professors Michael Kasha
and the late J. Herbert Taylor, and Professor Donald
Caspar, are members of the National Academy of Sciences.
Prof. Kasha has served on the influential National Science
Board. Distinguished visiting professors have included the
late William Rushton, and Nobel Laureate Robert Milliken.
The Molecular Biophysics Graduate Program and postdoctoral
mentorship have contributed to the Institute’s
position as a fertile training ground for over 200
scientists who now hold academic, industrial and government
positions. On November 18, 2001 the building housing the
Institute has been named Kasha Laboratory Building
(KLB) in honor of the founding director Prof.
Michael Kasha.
The Institute has developed Structural
Biology as a one of its research focuses. A generous grant
from the Lucille P. Markey Foundation and the State of
Florida supported substantial expansion of faculty and
research facilities in this area. With Structural Biology as a general
focus, students in the Molecular Biophysics Graduate
Program can work in labs with research programs ranging
from physical characterization of biopolymers to genetic
engineering, using interdisciplinary approaches and
state-of-the-art technology to investigate the structural
basis for biological function and dynamics.
In 2000, with a $1 million grant from
the FSU's Cornerstone
Program Professor Michael Chapman and others have
inaugurated the Center of Excellence (COE) for
Bio-Molecular Computer Modeling & Simulation Computational Biophysics as
another research focus. The Center establishes a bridge
between two strengths at Florida State University -
Experimental Structural
Biology, and School
of Computational Science. It is the focus of efforts to
build internationally renown programs in research and
training in the application of computational methods to an
understanding how biomolecules work.
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